| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BBta_2013 | hupC | BBta_2013 | BBta_1998 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.754 |
| BBta_2013 | hupF | BBta_2013 | BBta_2000 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic. | 0.710 |
| BBta_2013 | hupG | BBta_2013 | BBta_2001 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the HupG/HyaE family. | 0.905 |
| BBta_2013 | hupH | BBta_2013 | BBta_2002 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic. | 0.894 |
| BBta_2013 | hupI | BBta_2013 | BBta_2003 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Rubredoxin; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the rubredoxin family. | 0.870 |
| BBta_2013 | hupJ | BBta_2013 | BBta_2004 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydrogenase expression/formation; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic. | 0.921 |
| BBta_2013 | hupK | BBta_2013 | BBta_2005 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydrogenase expression/formation; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic. | 0.908 |
| BBta_2013 | hupS | BBta_2013 | BBta_1996 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Uptake hydrogenase small subunit precursor; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.752 |
| BBta_2013 | hupU-2 | BBta_2013 | BBta_1994 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Uptake hydrogenase accessory; Evidence: Function of strongly homologous gene; Localization: 9 : Periplasmic. | 0.982 |
| BBta_2013 | hypA-2 | BBta_2013 | BBta_2006 | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | Hydrogenase expression/formation; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.758 |
| hupC | BBta_2013 | BBta_1998 | BBta_2013 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | PAS/PAC sensor signal transduction histidine kinase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic. | 0.754 |
| hupC | hupF | BBta_1998 | BBta_2000 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic. | 0.944 |
| hupC | hupG | BBta_1998 | BBta_2001 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the HupG/HyaE family. | 0.984 |
| hupC | hupH | BBta_1998 | BBta_2002 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Hydrogenase expression/formation; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic. | 0.983 |
| hupC | hupI | BBta_1998 | BBta_2003 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Rubredoxin; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the rubredoxin family. | 0.884 |
| hupC | hupJ | BBta_1998 | BBta_2004 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Hydrogenase expression/formation; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic. | 0.914 |
| hupC | hupK | BBta_1998 | BBta_2005 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Hydrogenase expression/formation; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic. | 0.987 |
| hupC | hupS | BBta_1998 | BBta_1996 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Uptake hydrogenase small subunit precursor; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | 0.995 |
| hupC | hupU-2 | BBta_1998 | BBta_1994 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Uptake hydrogenase accessory; Evidence: Function of strongly homologous gene; Localization: 9 : Periplasmic. | 0.990 |
| hupC | hypA-2 | BBta_1998 | BBta_2006 | Ni/Fe-hydrogenase, 1 b-type cytochrome subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. | Hydrogenase expression/formation; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.768 |