STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthetase (Biotin synthase); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (350 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.976
bioF
8-amino-7-oxononanoate synthase; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
  
 0.952
BBta_4547
Putative Biotin--(acetyl-CoA-carboxylase) synthetase; (birA-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
  
 
 0.942
BBta_1580
Putative 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (Glycine C-acetyltransferase); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; PUBMED: 10712613.
 
  
 0.798
BBta_1920
Aminotransferase; Evidence: Function of strongly homologous gene; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.789
hemA
5-aminolevulinate synthase; Evidence: Function of strongly homologous gene.
  
 0.777
BBta_1928
Aminotransferase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.777
hemA-2
5-aminolevulinate synthase; Evidence: Function of strongly homologous gene.
  
 0.775
hemA-3
5-aminolevulinate synthase; Evidence: Function of homologous gene experimentally demonstrated in an other organism.
  
 0.765
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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