STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (473 aa)    
Predicted Functional Partners:
BBta_2188
Methionine synthase (B12-independent); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
  
 
 0.967
BBta_5267
Homocysteine methyltransferase (Methionine synthase); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
  
 
 0.967
BBta_5702
Hypothetical protein; Methionine synthase domain; Evidence: Similar to previously reported genes of unknown function.
  
 
 0.967
metH
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.961
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.933
BBta_0633
Putative cysteine synthase (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (CSase); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.931
metZ
O-succinylhomoserine sulfhydrylase (OSH sulfhydrylase); Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.925
oahs
O-acetylhomoserine sulfhydrolase; Evidence: Function of strongly homologous gene; Localization: 2 : Cytoplasmic.
  
 0.925
metC-2
Cystathionine beta-lyase; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
  
 0.925
BBta_3953
Cystathionine beta-lyase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic.
  
 0.925
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.