STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligA-2DNA ligase (Polydeoxyribonucleotide synthase (NAD+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (716 aa)    
Predicted Functional Partners:
BBta_0798
Putative DNA ligase, ATP-dependent; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
 0.917
uvrD
ATP-dependent DNA helicase, Rep family; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic.
 
  
 0.884
leuS
leucyl-tRNA synthetase; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 
 0.871
BBta_7513
ATP-dependent DNA helicase, Rep family; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.810
uvrA
UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 
 0.790
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
 
   
 0.752
pheT
phenylalanyl-tRNA synthetase beta subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.739
recN
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.730
pheS
phenylalanyl-tRNA synthetase, alpha subunit; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 2 : Cytoplasmic; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
  
 0.714
ruvB
Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
   
 0.714
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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