STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pntA2-2Nicotinamide nucleotide transhydrogenase, subunit alpha1; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein. (375 aa)    
Predicted Functional Partners:
pntB
Pyridine nucleotide transhydrogenase (proton pump), beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 0.999
pntA2
Nicotinamide nucleotide transhydrogenase, subunit alpha2; Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein.
 
 0.999
nadK
Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.921
cobB-3
Putative transciptional regulatory Sir2-family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
     
 0.911
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.909
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.908
BBta_3495
NH(3)-dependent NAD(+) synthetase; (NadE-like); Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Localization: 2 : Cytoplasmic; In the C-terminal section; belongs to the NAD synthetase family.
     
 0.908
BBta_4079
Protein mazG; Evidence: Function of strongly homologous gene.
    
  0.902
BBta_7348
Putative mutT/Nudix hydrolase family protein; Putative NADH pyrophosphatase; Evidence: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
  0.900
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
    0.648
Your Current Organism:
Bradyrhizobium sp. BTAi1
NCBI taxonomy Id: 288000
Other names: B. sp. BTAi1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.