AL038_02275 protein (Beggiatoa leptomitoformis)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Score

AL038_02275

Acyl-CoA dehydrogenase. (595 aa)

Predicted Functional Partners:

AL038_13070

0.921

AL038_10830

0.815

AL038_13065

0.802

AL038_12545

0.787

AL038_03380

0.730

AL038_07125

0.715

AL038_10825

0.676

AL038_12170

0.608

AL038_02860

0.572

AL038_02280

0.558

Your Current Organism:

Beggiatoa leptomitoformis

NCBI taxonomy Id: 288004
Other names: B. leptomitoformis, Beggiatoa leptomitiformis, Beggiatoa leptomitoformis Dubinina et al. 2017, Beggiatoa sp. D-402, DSM 14946, UNIQEM U 779, strain D-402

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
AL038_02275	AL038_02280	Acyl-CoA dehydrogenase.	Acyl-CoA dehydrogenase.	0.558
AL038_02275	AL038_02860	Acyl-CoA dehydrogenase.	Uncharacterized protein.	0.572
AL038_02275	AL038_03380	Acyl-CoA dehydrogenase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.730
AL038_02275	AL038_07125	Acyl-CoA dehydrogenase.	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	0.715
AL038_02275	AL038_10825	Acyl-CoA dehydrogenase.	Acyl-CoA synthetase.	0.676
AL038_02275	AL038_10830	Acyl-CoA dehydrogenase.	Enoyl-CoA hydratase.	0.815
AL038_02275	AL038_12170	Acyl-CoA dehydrogenase.	AMP-binding domain-containing protein.	0.608
AL038_02275	AL038_12545	Acyl-CoA dehydrogenase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.787
AL038_02275	AL038_13065	Acyl-CoA dehydrogenase.	Electron transfer flavoprotein subunit beta.	0.802
AL038_02275	AL038_13070	Acyl-CoA dehydrogenase.	Electron transfer flavoprotein subunit alpha.	0.921
AL038_02280	AL038_02275	Acyl-CoA dehydrogenase.	Acyl-CoA dehydrogenase.	0.558
AL038_02280	AL038_02860	Acyl-CoA dehydrogenase.	Uncharacterized protein.	0.572
AL038_02280	AL038_03380	Acyl-CoA dehydrogenase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.963
AL038_02280	AL038_07125	Acyl-CoA dehydrogenase.	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	0.664
AL038_02280	AL038_10825	Acyl-CoA dehydrogenase.	Acyl-CoA synthetase.	0.572
AL038_02280	AL038_10830	Acyl-CoA dehydrogenase.	Enoyl-CoA hydratase.	0.885
AL038_02280	AL038_12170	Acyl-CoA dehydrogenase.	AMP-binding domain-containing protein.	0.608
AL038_02280	AL038_12545	Acyl-CoA dehydrogenase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.981
AL038_02280	AL038_13065	Acyl-CoA dehydrogenase.	Electron transfer flavoprotein subunit beta.	0.782
AL038_02280	AL038_13070	Acyl-CoA dehydrogenase.	Electron transfer flavoprotein subunit alpha.	0.986

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.822

expected number of edges:

16

PPI enrichment p-value:

9.64e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070403

NAD+ binding

3 of 4

2.39

1.74

0.00055

GO:0008410

CoA-transferase activity

3 of 9

2.04

1.43

0.0017

GO:0003857

3-hydroxyacyl-CoA dehydrogenase activity

2 of 2

2.52

1.2

0.0064

GO:0016616

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

4 of 47

1.45

1.1

0.0027

GO:0004300

enoyl-CoA hydratase activity

2 of 3

2.34

1.1

0.0092

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1889

Mixed, incl. Coenzyme A transferase, and Dioxygenase

5 of 11

2.18

3.39

1.02e-07

CL:1865

Mixed, incl. Degradation of aromatic compounds, and Coenzyme A transferase

6 of 23

1.94

3.28

2.70e-08

CL:1511

Carbon metabolism, and Oxidoreductase activity

11 of 200

1.26

2.04

1.56e-11

CL:1706

NAD+ binding, and Beta-ketoacyl synthase, N-terminal domain

3 of 13

1.88

1.42

0.0014

CL:1700

Mixed, incl. Enoyl-CoA hydratase/isomerase, and Oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor

4 of 34

1.59

1.4

0.00065

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00650

Butanoate metabolism

8 of 52

1.71

3.43

6.57e-11

map00362

Benzoate degradation

4 of 35

1.58

1.55

0.00022

map00071

Fatty acid degradation

3 of 17

1.77

1.5

0.00070

map00281

Geraniol degradation

2 of 3

2.34

1.48

0.0017

map00072

Synthesis and degradation of ketone bodies

2 of 10

1.82

1.05

0.0083

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005777

Peroxisome

3 of 13

1.88

1.25

0.0034

GOCC:0009346

Citrate lyase complex

2 of 4

2.22

1.02

0.0125

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00725

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain

3 of 4

2.39

1.8

0.00042

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006176

3-hydroxyacyl-CoA dehydrogenase, NAD binding

3 of 4

2.39

1.59

0.0011

IPR006108

3-hydroxyacyl-CoA dehydrogenase, C-terminal

3 of 4

2.39

1.59

0.0011

IPR004165

Coenzyme A transferase family I

3 of 6

2.22

1.56

0.0011

IPR008927

6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily

3 of 16

1.79

1.07

0.0075

IPR037171

NagB/RpiA transferase-like

3 of 22

1.65

0.91

0.0141

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00882

Coenzyme A transferase

3 of 6

2.22

1.92

0.00020

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