STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HypFCarbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (757 aa)    
Predicted Functional Partners:
HypE
Hydrogenase expression/formation protein HypE.
 
 
 0.976
HypD
Hydrogenase maturation factor; Belongs to the HypD family.
 
  
 0.891
HypC
Hydrogenase assembly protein HypC.
 
 
 0.867
hypA
Hydrogenase maturation factor HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.860
HypB
Hydrogenase accessory protein HypB.
 
   
 0.810
AL038_04735
Hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.573
AL038_14805
Hydrogenase.
     
 0.537
AL038_04720
Ni/Fe hydrogenase.
 
 
 
 0.463
AL038_01155
Hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.419
Your Current Organism:
Beggiatoa leptomitoformis
NCBI taxonomy Id: 288004
Other names: B. leptomitoformis, Beggiatoa leptomitiformis, Beggiatoa leptomitoformis Dubinina et al. 2017, Beggiatoa sp. D-402, DSM 14946, UNIQEM U 779, strain D-402
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.