STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABY22109.1Multidrug resistance ABC transporter ATP-binding and permease protein. (914 aa)    
Predicted Functional Partners:
gluA
Glutamate transport ATP-binding protein.
 
     
0.792
ABY22110.1
Multidrug/protein/lipid ABC transporter family, ATP-binding and permease protein.
 
    
0.786
ABY24265.1
Heterocyst glycolipid synthase.
  
 0.669
moeB
Molybdopterin biosynthesis protein.
  
 0.524
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
   0.503
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
   0.489
arc
ATPases of the AAA+ class; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
  0.458
acuC
Acetoin utilization protein.
   
 0.431
ABY23152.1
Intracellular protease, ThiJ/PfpI family.
  
  0.429
glnQ
Glutamine transport ATP-binding protein.
 
     
0.421
Your Current Organism:
Renibacterium salmoninarum
NCBI taxonomy Id: 288705
Other names: R. salmoninarum ATCC 33209, Renibacterium salmoninarum ATCC 33209, Renibacterium salmoninarum str. ATCC 33209, Renibacterium salmoninarum strain ATCC 33209
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