node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABY22639.1 | ABY23461.1 | RSal33209_0896 | RSal33209_1725 | Cystathionine beta-synthase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.914 |
ABY22639.1 | ABY23828.1 | RSal33209_0896 | RSal33209_2096 | Cystathionine beta-synthase. | Phosphoserine phosphatase. | 0.928 |
ABY22639.1 | ABY24773.1 | RSal33209_0896 | RSal33209_3052 | Cystathionine beta-synthase. | Threonine dehydratase. | 0.944 |
ABY22639.1 | ABY25037.1 | RSal33209_0896 | RSal33209_3325 | Cystathionine beta-synthase. | Serine acetyltransferase. | 0.979 |
ABY22639.1 | glyA | RSal33209_0896 | RSal33209_0271 | Cystathionine beta-synthase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.940 |
ABY22639.1 | glyA-2 | RSal33209_0896 | RSal33209_1724 | Cystathionine beta-synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.940 |
ABY22639.1 | thrB | RSal33209_0896 | RSal33209_1431 | Cystathionine beta-synthase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.822 |
ABY22639.1 | trpA | RSal33209_0896 | RSal33209_2332 | Cystathionine beta-synthase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.917 |
ABY22639.1 | trpB | RSal33209_0896 | RSal33209_2333 | Cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.910 |
ABY23461.1 | ABY22639.1 | RSal33209_1725 | RSal33209_0896 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Cystathionine beta-synthase. | 0.914 |
ABY23461.1 | ABY23828.1 | RSal33209_1725 | RSal33209_2096 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase. | 0.912 |
ABY23461.1 | ABY24773.1 | RSal33209_1725 | RSal33209_3052 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase. | 0.952 |
ABY23461.1 | ABY25037.1 | RSal33209_1725 | RSal33209_3325 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine acetyltransferase. | 0.910 |
ABY23461.1 | gcvP | RSal33209_1725 | RSal33209_1721 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.875 |
ABY23461.1 | glyA | RSal33209_1725 | RSal33209_0271 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.968 |
ABY23461.1 | glyA-2 | RSal33209_1725 | RSal33209_1724 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.983 |
ABY23461.1 | thrB | RSal33209_1725 | RSal33209_1431 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.847 |
ABY23461.1 | trpA | RSal33209_1725 | RSal33209_2332 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.905 |
ABY23461.1 | trpB | RSal33209_1725 | RSal33209_2333 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
ABY23828.1 | ABY22639.1 | RSal33209_2096 | RSal33209_0896 | Phosphoserine phosphatase. | Cystathionine beta-synthase. | 0.928 |