STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GgtGamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)    
Predicted Functional Partners:
EI16_06470
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.936
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.913
gshB
Glutathione synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
    
 0.912
gshB-2
The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
    
 0.912
EI16_02745
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.909
PepN
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.909
EI16_06465
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.909
EI16_05105
Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
EI16_08360
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
EI16_08370
Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
Your Current Organism:
Hydrogenovibrio marinus
NCBI taxonomy Id: 28885
Other names: DSM 11271, H. marinus, Hydrogenivibrio marinus, JCM 7688, strain MH-110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.