STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG05980.1KEGG: mhu:Mhun_0816 hypothetical protein; SPTR: Putative uncharacterized protein. (155 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.683
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.623
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.574
EJG08383.1
PFAM: DnaJ domain; InterPro IPR001623; KEGG: mem:Memar_0880 heat shock protein DnaJ domain-containing protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein.
  
 
 0.574
rpl10e
PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L10.e; COGs: COG0197 Ribosomal protein L16/L10E; HAMAP: 50S ribosomal protein L10e; InterPro IPR016180; KEGG: mpl:Mpal_1074 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.498
EJG07995.1
Peptidase S16, Lon-like protease; PFAM: Magnesium chelatase, subunit ChlI; Sigma-54 interaction domain; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; COGs: COG1067 ATP-dependent protease; InterPro IPR003593:IPR004663:IPR000523:IPR008269; KEGG: mem:Memar_0276 ATP-dependent protease Lon; PFAM: Peptidase S16, lon C-terminal; Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Lon-B peptidase, Serine peptidase, MEROPS family S16; TIGRFAM: Peptidase S16, archaeal lon homologs; Belongs to the peptidase S16 family.
  
  
 0.496
EJG08116.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: mem:Memar_0335 glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: L-glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
    
 
 0.465
rlmH
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
       0.464
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
    
 
 0.416
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.