Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG05980.1KEGG: mhu:Mhun_0816 hypothetical protein; SPTR: Putative uncharacterized protein. (155 aa)    
Predicted Functional Partners:
EJG06819.1
PFAM: CS domain; InterPro IPR017447; KEGG: mpi:Mpet_2356 hypothetical protein; PFAM: CS; SPTR: Putative uncharacterized protein.
     
 0.778
EJG07735.1
Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: mem:Memar_1986 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; manually curated; Belongs to the small heat shock protein (HSP20) family.
     
  0.744
EJG08116.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: mem:Memar_0335 glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: L-glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
    
 
 0.701
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.665
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.582
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.567
EJG08383.1
PFAM: DnaJ domain; InterPro IPR001623; KEGG: mem:Memar_0880 heat shock protein DnaJ domain-containing protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein.
  
 
 0.567
rpl10e
PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L10.e; COGs: COG0197 Ribosomal protein L16/L10E; HAMAP: 50S ribosomal protein L10e; InterPro IPR016180; KEGG: mpl:Mpal_1074 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.546
EJG06818.1
PFAM: Bacterial regulatory protein, arsR family; COGs: COG1777 transcriptional regulator protein; InterPro IPR001845; KEGG: mpl:Mpal_2059 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family.
     
 0.535
rlmH
Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
       0.459
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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