STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06082.1Riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: riboflavin synthase; COGs: COG1731 riboflavin synthase; InterPro IPR002180:IPR006399; KEGG: mpi:Mpet_0320 riboflavin synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; SPTR: Riboflavin synthase; TIGRFAM: Riboflavin synthase, archaeal. (153 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
  
  0.999
EJG08301.1
PFAM: MarR family; Domain of unknown function DUF120; COGs: COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon; InterPro IPR000835:IPR002834; KEGG: mbn:Mboo_0159 hypothetical protein; PFAM: Riboflavin kinase, CTP-dependent, archaeal; HTH transcriptional regulator, MarR; SPTR: Riboflavin kinase.
    
  0.984
EJG06083.1
PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mem:Memar_0056 aminotransferase, class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Phosphoserine aminotransferase apoenzyme / L-aspartate aminotransferase apoenzyme.
       0.936
EJG06080.1
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: mbn:Mboo_0056 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase, class I and II.
       0.801
EJG08300.1
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
   
 0.742
purE
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.657
EJG07239.1
PFAM: Uncharacterized protein conserved in archaea (DUF2111); COGs: COG4048 conserved hypothetical protein; InterPro IPR012029; KEGG: mem:Memar_1649 hypothetical protein; PFAM: Uncharacterised conserved protein UCP006557, signal transduction; SPTR: Putative uncharacterized protein.
  
     0.603
EJG06079.1
Putative PAS/PAC sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2202 FOG: PAS/PAC domain; InterPro IPR000014:IPR003661:IPR013656; KEGG: geb:GM18_3556 putative PAS/PAC sensor protein; PFAM: PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS.
       0.590
EJG06969.1
PFAM: Amidohydrolase family; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: mem:Memar_1195 amidohydrolase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase.
 
     0.570
EJG08149.1
PFAM: ArsR transcriptional regulator; COGs: COG4860 conserved hypothetical protein; InterPro IPR014517; KEGG: mbn:Mboo_2245 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.554
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.