Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG06087.1Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: mem:Memar_0052 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein. (199 aa)    
Predicted Functional Partners:
EJG06244.1
Rhodanese-like protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: mpi:Mpet_2048 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein.
 
 0.950
EJG07396.1
Rhodanese-like protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: mem:Memar_2326 beta-lactamase domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Beta-lactamase domain protein.
 
 0.950
EJG06378.1
PFAM: Rhodanese-like domain; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: mem:Memar_2054 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein.
 
 0.945
EJG06088.1
PFAM: Domain of unknown function DUF123; COGs: COG1833 conserved hypothetical protein; InterPro IPR002837; KEGG: mba:Mbar_A0396 endonuclease III; PFAM: Protein of unknown function DUF123; SPTR: Endonuclease III.
       0.790
EJG06089.1
PFAM: NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mem:Memar_0050 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase.
       0.773
EJG07226.1
PFAM: Protein of unknown function DUF99; COGs: COG1628 conserved hypothetical protein; HAMAP: UPF0215 protein; InterPro IPR002802; KEGG: mem:Memar_1663 hypothetical protein; PFAM: Protein of unknown function DUF99; SPTR: UPF0215 protein Memar_1663; Belongs to the UPF0215 family.
       0.666
EJG06552.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: mpl:Mpal_0439 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphogl [...]
 
  
 0.644
EJG06086.1
PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC; COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: mem:Memar_0053 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC; SPTR: Hydroxymethylpyrimidine synthase; TIGRFAM: Thiamine biosynthesis protein ThiC.
  
    0.569
EJG08172.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: mem:Memar_1336 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: UBA/THIF-type NAD/FAD binding protein.
 
  
 0.500
EJG07925.1
PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; InterPro IPR004360; KEGG: mpi:Mpet_0484 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase.
  
 0.498
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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