STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06090.1PFAM: Domain of unknown function (DUF1805); COGs: COG3377 conserved hypothetical protein; InterPro IPR014931; KEGG: mbn:Mboo_0039 hypothetical protein; PFAM: Protein of unknown function DUF1805; SPTR: Putative uncharacterized protein. (156 aa)    
Predicted Functional Partners:
EJG06091.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013655:IPR013656; KEGG: mpl:Mpal_0273 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold-3; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction re [...]
       0.494
EJG08206.1
5'-Nucleotidase domain-containing protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: mem:Memar_1147 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: 5'-Nucleotidase domain protein.
  
    0.418
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
       0.407
EJG07589.1
PFAM: Putative RNA methylase family UPF0020; TIGRFAM: TIGR01177 family protein; COGs: COG1041 DNA modification methylase; InterPro IPR000241; KEGG: mem:Memar_1059 putative RNA methylase; PFAM: Putative RNA methylase; SPTR: N2-methylguanosine tRNA methyltransferase.
       0.400
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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