STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cobDCobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (306 aa)    
Predicted Functional Partners:
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 
 0.998
EJG06870.1
PFAM: Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: mem:Memar_1447 putative L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase.
 
  
 0.992
EJG06871.1
5-deoxyadenosylcobinamide phosphate nucleotidyltransferase; TIGRFAM: TIGR00454 family protein; COGs: COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase; KEGG: mem:Memar_1446 5-deoxyadenosylcobinamide phosphate nucleotidyltransferase; SPTR: Molybdenum cofactor guanylyltransferase.
    
  0.987
EJG08295.1
Protein of unknown function DUF105; PFAM: Cysteine-rich small domain; Adenosylcobinamide amidohydrolase; COGs: COG1865 conserved hypothetical protein; InterPro IPR002808:IPR007212; KEGG: mla:Mlab_0705 hypothetical protein; PFAM: Adenosylcobinamide amidohydrolase, CbiZ; Cysteine-rich small domain; SPTR: Putative uncharacterized protein.
 
  
 0.978
EJG07462.1
PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: mbn:Mboo_1225 precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; SPTR: Precorrin-8X methylmutase CbiC/CobH.
 
 
 0.972
EJG06109.1
Protein of unknown function DUF343; PFAM: Trm112p-like protein; InterPro IPR005651; KEGG: mem:Memar_0006 hypothetical protein; PFAM: Protein of unknown function DUF343; SPTR: Putative uncharacterized protein.
       0.946
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.946
EJG07463.1
precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR000878; KEGG: mpi:Mpet_1758 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; manually curated.
 
  
 0.946
EJG06108.1
KEGG: mem:Memar_0007 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.938
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.921
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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