STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). (701 aa)    
Predicted Functional Partners:
EJG06131.1
PFAM: Calcineurin-like phosphoesterase; CHAD domain; TIGRFAM: phosphoesterase, MJ0936 family; COGs: COG5607 conserved hypothetical protein; InterPro IPR007899:IPR004843; KEGG: mpi:Mpet_1489 CHAD domain-containing protein; PFAM: CHAD; Metallophosphoesterase; SPTR: CHAD domain containing protein.
 
   
 0.963
EJG06132.1
Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG0248 Exopolyphosphatase; InterPro IPR006674; KEGG: mpi:Mpet_1490 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Phosphatase, Ppx/GppA family.
 
  
 0.956
EJG07316.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR005672:IPR000515; KEGG: mpi:Mpet_1485 phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; Phosphate transport system [...]
     
 0.947
EJG06699.1
PFAM: HD domain; Ppx/GppA phosphatase family; COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR006674; KEGG: mac:MA0083 exopolyphosphatase; PFAM: Ppx/GppA phosphatase; Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Exopolyphosphatase.
 
  
 0.854
EJG07008.1
PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: mmh:Mmah_0747 polyphosphate:AMP phosphotransferase; PFAM: Polyphosphate kinase 2; SPTR: Polyphosphate:AMP phosphotransferase; TIGRFAM: polyphosphate:AMP phosphotransferase.
 
  
 0.758
EJG06133.1
PFAM: Permease family; TIGRFAM: uracil-xanthine permease; COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR006042; KEGG: mpi:Mpet_0070 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil-xanthine permease; TIGRFAM: Xanthine/uracil permease.
     
 0.630
EJG06129.1
PFAM: Acyltransferase family; InterPro IPR002656; KEGG: mem:Memar_0478 acyltransferase 3; PFAM: Acyltransferase 3; SPTR: Acyltransferase 3.
  
    0.561
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.556
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006436; KEGG: mpl:Mpal_2790 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; SPTR: Glyceraldehyde-3-phosph [...]
     
 0.520
EJG06134.1
Putative signal transduction histidine kinase; PFAM: Natural resistance-associated macrophage protein; 5TMR of 5TMR-LYT; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR011620; KEGG: mpi:Mpet_2152 signal transduction histidine kinase LytS; PFAM: Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SPTR: Signal transduction histidine kinase, LytS.
       0.503
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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