STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06131.1PFAM: Calcineurin-like phosphoesterase; CHAD domain; TIGRFAM: phosphoesterase, MJ0936 family; COGs: COG5607 conserved hypothetical protein; InterPro IPR007899:IPR004843; KEGG: mpi:Mpet_1489 CHAD domain-containing protein; PFAM: CHAD; Metallophosphoesterase; SPTR: CHAD domain containing protein. (590 aa)    
Predicted Functional Partners:
EJG06132.1
Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG0248 Exopolyphosphatase; InterPro IPR006674; KEGG: mpi:Mpet_1490 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Phosphatase, Ppx/GppA family.
  
  0.991
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
 
   
 0.963
rpl40e
PFAM: Ribosomal L40e family; HAMAP: 50S ribosomal protein L40e; InterPro IPR001975; KEGG: mbn:Mboo_0238 50S ribosomal protein L40e; PFAM: Ribosomal protein L40e; SPTR: 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
 0.891
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.877
EJG07741.1
PFAM: Exonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; COGs: COG1570 Exonuclease VII large subunit; HAMAP: Exodeoxyribonuclease 7 large subunit; InterPro IPR003753:IPR004365:IPR020579; KEGG: mem:Memar_1979 exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Exodeoxyribonuclease VII large subunit; TIGRFAM: Exonuclease VII, large subunit.
  
    0.873
EJG06316.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: mpi:Mpet_0609 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
  
 
 0.872
EJG07316.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR005672:IPR000515; KEGG: mpi:Mpet_1485 phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; Phosphate transport system [...]
 
     0.865
EJG07889.1
PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain; COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029:IPR011488; KEGG: mem:Memar_2051 translation initiation factor IF-2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2, alpha subunit; Ribosomal protein S1, RNA binding domain; SPTR: Translation initiation factor 2 subunit alpha (AeIF-2a).
   
 0.864
EJG06699.1
PFAM: HD domain; Ppx/GppA phosphatase family; COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR006674; KEGG: mac:MA0083 exopolyphosphatase; PFAM: Ppx/GppA phosphatase; Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Exopolyphosphatase.
    
  0.862
ppk-2
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family.
 
   
 0.845
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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