STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06132.1Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG0248 Exopolyphosphatase; InterPro IPR006674; KEGG: mpi:Mpet_1490 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Phosphatase, Ppx/GppA family. (196 aa)    
Predicted Functional Partners:
EJG06131.1
PFAM: Calcineurin-like phosphoesterase; CHAD domain; TIGRFAM: phosphoesterase, MJ0936 family; COGs: COG5607 conserved hypothetical protein; InterPro IPR007899:IPR004843; KEGG: mpi:Mpet_1489 CHAD domain-containing protein; PFAM: CHAD; Metallophosphoesterase; SPTR: CHAD domain containing protein.
  
  0.991
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
 
  
 0.956
EJG07316.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR005672:IPR000515; KEGG: mpi:Mpet_1485 phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; Phosphate transport system [...]
     
 0.947
ppk-2
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.821
EJG06133.1
PFAM: Permease family; TIGRFAM: uracil-xanthine permease; COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR006042; KEGG: mpi:Mpet_0070 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil-xanthine permease; TIGRFAM: Xanthine/uracil permease.
     
 0.621
EJG06129.1
PFAM: Acyltransferase family; InterPro IPR002656; KEGG: mem:Memar_0478 acyltransferase 3; PFAM: Acyltransferase 3; SPTR: Acyltransferase 3.
       0.557
EJG06134.1
Putative signal transduction histidine kinase; PFAM: Natural resistance-associated macrophage protein; 5TMR of 5TMR-LYT; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR011620; KEGG: mpi:Mpet_2152 signal transduction histidine kinase LytS; PFAM: Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SPTR: Signal transduction histidine kinase, LytS.
  
    0.528
EJG06847.1
PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain; COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR001667:IPR010766:IPR004097; KEGG: mem:Memar_0491 putative manganese-dependent inorganic pyrophosphatase; PFAM: Cystathionine beta-synthase, core; Phosphoesterase, RecJ-like; DRTGG; DHHA2; SMART: Cystathionine beta-synthase, core; SPTR: Inorganic diphosphatase.
    
  0.512
EJG07008.1
PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: mmh:Mmah_0747 polyphosphate:AMP phosphotransferase; PFAM: Polyphosphate kinase 2; SPTR: Polyphosphate:AMP phosphotransferase; TIGRFAM: polyphosphate:AMP phosphotransferase.
 
  
 0.495
tyrS
Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
 
     0.451
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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