STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06151.1Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: pmx:PERMA_0670 protein hit; PFAM: Histidine triad (HIT) protein; SPTR: Protein hit. (122 aa)    
Predicted Functional Partners:
EJG06316.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: mpi:Mpet_0609 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
  
 0.675
EJG06142.1
PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; Domain of unknown function (DUF3427); COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001:IPR001650:IPR006935; KEGG: mem:Memar_0449 type III restriction enzyme, res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; DNA/RNA helicase, C-terminal; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Type III restriction enzyme, res subunit.
 
 
  0.621
EJG07778.1
PFAM: Oxidoreductase molybdopterin binding domain; InterPro IPR000572; KEGG: mla:Mlab_1026 hypothetical protein; PFAM: Oxidoreductase, molybdopterin binding; SPTR: Putative uncharacterized protein.
   
  0.585
EJG06152.1
Hypothetical protein.
       0.576
EJG08129.1
PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin); COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: mpl:Mpal_2571 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein-tyrosine phosphatase, low molecular weight.
  
 
  0.558
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
 
 
  0.528
EJG07557.1
PFAM: PUA domain; Phosphoadenosine phosphosulfate reductase family; TIGRFAM: uncharacterized domain 2; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR004521:IPR002478:IPR002500; KEGG: mpl:Mpal_2089 hypothetical protein; PFAM: Phosphoadenosine phosphosulphate reductase; Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: Phosphoadenosine phosphosulfate reductase.
  
 
  0.508
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
    
 0.465
EJG07268.1
PFAM: Transcription factor TFIID (or TATA-binding protein, TBP); COGs: COG2101 TATA-box binding protein (TBP) component of TFIID and TFIIIB; InterPro IPR000814; KEGG: tba:TERMP_01858 TatA-box binding protein; PFAM: TATA-box binding; SPTR: Transcription factor TFIID (Or TATA-binding protein, TBP).
   
 0.465
tbp-2
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
 0.465
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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