STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06188.1NUDIX hydrolase; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375:IPR015376:IPR000086; KEGG: mbn:Mboo_0886 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal; SPTR: NUDIX hydrolase. (280 aa)    
Predicted Functional Partners:
EJG08206.1
5'-Nucleotidase domain-containing protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: mem:Memar_1147 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: 5'-Nucleotidase domain protein.
 
  
  0.934
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
   
 
  0.925
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.921
EJG07083.1
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
     
 0.919
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.918
EJG06802.1
PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain; COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; InterPro IPR004820:IPR006418:IPR004821; KEGG: mbu:Mbur_2370 nicotinamide-nucleotide adenylyltransferase; PFAM: Cytidylyltransferase; SPTR: Nicotinamide-nucleotide adenylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related.
     
 0.913
EJG07668.1
PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase; COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR002638; KEGG: mbn:Mboo_0766 quinolinate phosphoribosyl transferase; PFAM: Quinolinate phosphoribosyl transferase; SPTR: Quinolinate phosphoribosyl transferase.
    
 0.663
EJG06316.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: mpi:Mpet_0609 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
    
 0.630
EJG06189.1
PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: mpi:Mpet_1183 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
       0.598
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
 
  0.558
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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