Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EJG06205.1PFAM: Protein of unknown function (DUF432); COGs: COG2430 conserved hypothetical protein; InterPro IPR007366; KEGG: mem:Memar_1776 hypothetical protein; PFAM: Protein of unknown function DUF432; SPTR: Putative uncharacterized protein. (234 aa)    
Predicted Functional Partners:
EJG06204.1
PFAM: Mechanosensitive ion channel; COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: afu:AF1546 hypothetical protein; PFAM: Mechanosensitive ion channel MscS; SPTR: Uncharacterized mscS family protein AF_1546.
       0.799
EJG06203.1
PFAM: PBS lyase HEAT-like repeat; InterPro IPR004155; KEGG: mbn:Mboo_0125 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT-like repeat; SPTR: PBS lyase HEAT domain protein repeat-containing protein.
       0.778
EJG06202.1
PBS lyase HEAT domain protein repeat-containing protein; PFAM: PBS lyase HEAT-like repeat; COGs: COG1413 FOG: HEAT repeat; InterPro IPR004155; KEGG: mem:Memar_2129 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat; SPTR: PBS lyase HEAT domain protein repeat-containing protein.
       0.671
polC
DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
       0.540
EJG06206.1
PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: rmr:Rmar_0641 peptidylprolyl isomerase FKBP-type; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase.
       0.490
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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