Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EJG06252.1Phospholipase D/transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: mem:Memar_2448 phospholipase D/transphosphatidylase; SPTR: Phospholipase D/Transphosphatidylase. (551 aa)    
Predicted Functional Partners:
EJG06601.1
Small GTP-binding protein; PFAM: GTPase of unknown function; COGs: COG0486 GTPase; InterPro IPR002917:IPR005225; KEGG: mpl:Mpal_2664 small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
   
 0.897
EJG07316.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR005672:IPR000515; KEGG: mpi:Mpet_1485 phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; Phosphate transport system [...]
     
 0.833
EJG06408.1
PFAM: Tubulin/FtsZ family, GTPase domain; COGs: COG0206 Cell division GTPase; InterPro IPR003008; KEGG: mem:Memar_0556 cell division GTPase-like protein; PFAM: Tubulin/FtsZ, GTPase domain; SPTR: Cell division GTPase-like protein.
  
   
 0.713
EJG07823.1
PFAM: CDP-alcohol phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: mem:Memar_1904 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.684
carS
UPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
  
 0.666
EJG07702.1
PFAM: DHHA1 domain; COGs: COG2404 phosphohydrolase (DHH superfamily); InterPro IPR003156; KEGG: mem:Memar_2015 phosphoesterase, DHHA1; PFAM: Phosphoesterase, DHHA1; SPTR: Phosphoesterase, DHHA1.
 
     0.665
EJG07857.1
PFAM: CDP-alcohol phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: mem:Memar_1397 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.656
EJG06251.1
PFAM: Amino acid kinase family; COGs: COG2054 Uncharacterized kinase related to aspartokinase uridylate kinase; InterPro IPR001048; KEGG: mpl:Mpal_2593 aspartate/glutamate/uridylate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Aspartate/glutamate/uridylate kinase.
       0.653
EJG07934.1
Phosphoesterase PA-phosphatase related protein; PFAM: PAP2 superfamily; InterPro IPR000326; KEGG: atm:ANT_23660 phosphatase; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: Phosphatase.
   
 0.648
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 0.646
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.