STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06334.1PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; COGs: COG1230 Co/Zn/Cd efflux system component; InterPro IPR002524; KEGG: mbn:Mboo_0978 cation diffusion facilitator family transporter; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein. (298 aa)    
Predicted Functional Partners:
EJG08020.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027; KEGG: mbn:Mboo_2329 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.698
EJG06050.1
PFAM: V-type ATPase 116kDa subunit family; COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: mhu:Mhun_1775 V-type ATPase, 116 kDa subunit; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: V-type ATPase, 116 kDa subunit; Belongs to the V-ATPase 116 kDa subunit family.
    
 
 0.635
EJG08006.1
PFAM: V-type ATPase 116kDa subunit family; COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: mem:Memar_0282 V-type ATP synthase subunit I; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: V-type ATPase, 116 kDa subunit; Belongs to the V-ATPase 116 kDa subunit family.
    
 
 0.635
EJG06134.1
Putative signal transduction histidine kinase; PFAM: Natural resistance-associated macrophage protein; 5TMR of 5TMR-LYT; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR011620; KEGG: mpi:Mpet_2152 signal transduction histidine kinase LytS; PFAM: Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SPTR: Signal transduction histidine kinase, LytS.
  
 
 0.610
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.607
EJG06333.1
Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mem:Memar_2194 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; manually curated.
       0.555
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 
 0.540
EJG07516.1
KEGG: mem:Memar_2460 hypothetical protein; SPTR: Putative uncharacterized protein.
    
  0.530
EJG07904.1
Copper-translocating P-type ATPase; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR006403:IPR006416:IPR001757:IPR008250:IPR 005834; KEGG: mem:Memar_1352 copper-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Haloacid dehalogenase-like hydrolase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; AT [...]
 
  
 0.522
EJG07874.1
PFAM: E1-E2 ATPase; YHS domain; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR011017:IPR006122:IPR006403:IPR006416:IPR 001757:IPR006121:IPR008250:IPR005834:IPR007029; KEGG: mem:Memar_1873 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid [...]
  
  
 0.491
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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