STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06334.1PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; COGs: COG1230 Co/Zn/Cd efflux system component; InterPro IPR002524; KEGG: mbn:Mboo_0978 cation diffusion facilitator family transporter; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein. (298 aa)    
Predicted Functional Partners:
EJG07874.1
PFAM: E1-E2 ATPase; YHS domain; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR011017:IPR006122:IPR006403:IPR006416:IPR 001757:IPR006121:IPR008250:IPR005834:IPR007029; KEGG: mem:Memar_1873 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid [...]
  
  
 0.620
EJG07904.1
Copper-translocating P-type ATPase; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR006403:IPR006416:IPR001757:IPR008250:IPR 005834; KEGG: mem:Memar_1352 copper-translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; Haloacid dehalogenase-like hydrolase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; AT [...]
 
  
 0.603
EJG06333.1
Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mem:Memar_2194 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; manually curated.
       0.555
EJG07363.1
PFAM: AhpC/TSA family; COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: tam:Theam_0591 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen.
     
 0.515
EJG08129.1
PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin); COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: mpl:Mpal_2571 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein-tyrosine phosphatase, low molecular weight.
  
  
 0.513
eif2b
Translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
 
   0.494
EJG08020.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027; KEGG: mbn:Mboo_2329 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.478
EJG08260.1
PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mem:Memar_0167 cation diffusion facilitator family transporter; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein.
 
 
0.456
EJG06134.1
Putative signal transduction histidine kinase; PFAM: Natural resistance-associated macrophage protein; 5TMR of 5TMR-LYT; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR011620; KEGG: mpi:Mpet_2152 signal transduction histidine kinase LytS; PFAM: Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SPTR: Signal transduction histidine kinase, LytS.
  
  
 0.446
EJG06645.1
Zinc/iron permease; PFAM: ZIP Zinc transporter; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: mmh:Mmah_0656 zinc/iron permease; PFAM: Zinc/iron permease; SPTR: Zinc/iron permease.
   
 
 0.433
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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