STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06467.1PFAM: Methyl-coenzyme M reductase gamma subunit; TIGRFAM: methyl-coenzyme M reductase, gamma subunit; COGs: COG4057 Methyl coenzyme M reductase gamma subunit; InterPro IPR003178; KEGG: mpl:Mpal_2308 methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit; SPTR: Methyl-coenzyme M reductase, gamma subunit; TIGRFAM: Methyl-coenzyme M reductase, gamma subunit. (254 aa)    
Predicted Functional Partners:
EJG06466.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
 0.999
EJG06468.1
PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C; COGs: COG4056 Methyl coenzyme M reductase subunit C; InterPro IPR007687; KEGG: mpl:Mpal_2307 methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase, protein C; SPTR: Methyl-coenzyme M reductase I operon protein C; TIGRFAM: Methyl-coenzyme M reductase, protein C.
 
 
 0.999
EJG06470.1
PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit.
 
 0.999
EJG07654.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
 0.999
EJG06469.1
PFAM: Methyl-coenzyme M reductase operon protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D; COGs: COG4055 Methyl coenzyme M reductase subunit D; InterPro IPR003901; KEGG: mpl:Mpal_2306 methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase, protein D; SPTR: Methyl-coenzyme M reductase operon protein D; TIGRFAM: Methyl-coenzyme M reductase, protein D.
 
 
 0.998
EJG07656.1
PFAM: Methyl-coenzyme M reductase operon protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D; COGs: COG4055 Methyl coenzyme M reductase subunit D; InterPro IPR003901; KEGG: mem:Memar_0376 methyl-coenzyme M reductase, protein D; PFAM: Methyl-coenzyme M reductase, protein D; SPTR: Methyl-coenzyme M reductase, protein D; TIGRFAM: Methyl-coenzyme M reductase, protein D.
 
 
 0.995
EJG06361.1
PFAM: ABC transporter; TIGRFAM: methyl coenzyme M reductase system, component A2; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017669:IPR003439:IPR003593; KEGG: mbn:Mboo_2434 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; TIGRFAM: Methyl coenzyme M reductase system, component A2.
  
  
  0.993
EJG07657.1
PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0375 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit.
 
 0.993
mtrE
Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
 
 
 0.969
mtrA-2
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
 
 
 0.968
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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