STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfnAL-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (365 aa)    
Predicted Functional Partners:
EJG07848.1
ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG1821 ATP-utilizing protein (ATP-grasp superfamily); InterPro IPR003806; KEGG: mpl:Mpal_0581 protein of unknown function DUF201; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein.
 
  
 0.986
EJG07598.1
PFAM: Protein of unknown function DUF137; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; KEGG: mem:Memar_1234 hypothetical protein; PFAM: Protein of unknown function DUF137; SPTR: Pantothenate synthetase.
    
 0.984
EJG06080.1
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: mbn:Mboo_0056 aspartate aminotransferase; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase, class I and II.
  
 
 0.982
EJG07385.1
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: mbn:Mboo_1200 aminotransferase, class I and II; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase, class I and II.
  
 
 0.982
hisC
PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: Histidinol-phosphate aminotransferase; InterPro IPR005861:IPR004839; KEGG: mem:Memar_1902 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: Histidinol-phosphate aminotransferase.
    
 0.981
EJG07114.1
PFAM: Asparagine synthase; COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR001962; KEGG: mem:Memar_0774 asparagine synthase; PFAM: Asparagine synthase; SPTR: Asparagine synthase.
 
  
 0.978
argG
PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; InterPro IPR001518; KEGG: mbn:Mboo_0836 argininosuccinate synthase; PFAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.976
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.972
pyrB
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: mem:Memar_1689 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carba [...]
    
  0.971
EJG06553.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.954
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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