Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EJG06619.1Protein of unknown function DUF151; PFAM: Uncharacterised ACR, COG1259; COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: mem:Memar_1780 hypothetical protein; PFAM: Protein of unknown function DUF151; SPTR: Putative uncharacterized protein. (149 aa)    
Predicted Functional Partners:
EJG06618.1
PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein; COGs: COG0392 integral membrane protein; InterPro IPR005242; KEGG: mem:Memar_1781 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.724
hisE
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphatase; InterPro IPR008179; KEGG: mem:Memar_1779 phosphoribosyl-ATP pyrophosphohydrolase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP pyrophosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase.
       0.662
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.588
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
       0.569
tuf
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
       0.537
secG
Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
       0.526
EJG06612.1
PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367:IPR007167; KEGG: mem:Memar_1785 FeoA family protein; PFAM: Iron dependent repressor; Ferrous iron transporter, FeoA subunit; SMART: Iron dependent repressor; SPTR: FeoA family protein.
 
     0.525
rps10
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
       0.476
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
       0.460
EJG06617.1
PFAM: Protein of unknown function (DUF357); COGs: COG1849 conserved hypothetical protein; InterPro IPR007155; KEGG: mpl:Mpal_0117 protein of unknown function DUF357; PFAM: Protein of unknown function DUF357; SPTR: Putative uncharacterized protein.
       0.460
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: medium (46%) [HD]