STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06623.1PFAM: Protein of unknown function (DUF541); COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: mem:Memar_1773 hypothetical protein; PFAM: Protein of unknown function DUF541; SPTR: Putative uncharacterized protein. (245 aa)    
Predicted Functional Partners:
EJG06622.1
Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mem:Memar_1774 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein.
       0.603
EJG06624.1
Ion transport 2 domain protein; PFAM: Ion channel; InterPro IPR013099; KEGG: mem:Memar_1772 ion transport 2 domain-containing protein; PFAM: Ion transport 2; SPTR: Ion transport 2 domain protein.
       0.577
htpX
Protease htpX; PFAM: Peptidase family M48; COGs: COG0501 Zn-dependent protease with chaperone function; HAMAP: protease htpX; InterPro IPR001915; KEGG: mpl:Mpal_0594 heat shock protein HtpX; PFAM: Peptidase M48, Ste24p; SPTR: Protease HtpX homolog; Belongs to the peptidase M48B family.
 
    0.524
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
     0.489
EJG08206.1
5'-Nucleotidase domain-containing protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: mem:Memar_1147 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: 5'-Nucleotidase domain protein.
 
     0.476
hisE
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphatase; InterPro IPR008179; KEGG: mem:Memar_1779 phosphoribosyl-ATP pyrophosphohydrolase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP pyrophosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase.
 
     0.450
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
 
     0.431
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.407
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
       0.407
EJG07293.1
PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: mem:Memar_1721 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein.
       0.407
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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