Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EJG06624.1Ion transport 2 domain protein; PFAM: Ion channel; InterPro IPR013099; KEGG: mem:Memar_1772 ion transport 2 domain-containing protein; PFAM: Ion transport 2; SPTR: Ion transport 2 domain protein. (235 aa)    
Predicted Functional Partners:
EJG06661.1
Small GTP-binding protein; PFAM: GTPase of unknown function; TGS domain; TIGRFAM: small GTP-binding protein domain; COGs: COG1163 GTPase; InterPro IPR002917:IPR004095:IPR005225; KEGG: mem:Memar_1699 small GTP-binding protein; PFAM: TGS; GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
     
  0.688
EJG06252.1
Phospholipase D/transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: mem:Memar_2448 phospholipase D/transphosphatidylase; SPTR: Phospholipase D/Transphosphatidylase.
     
 0.615
EJG06623.1
PFAM: Protein of unknown function (DUF541); COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: mem:Memar_1773 hypothetical protein; PFAM: Protein of unknown function DUF541; SPTR: Putative uncharacterized protein.
       0.567
dnaK
Chaperone protein dnaK; Acts as a chaperone.
     
 0.564
EJG07341.1
PFAM: Glycerophosphoryl diester phosphodiesterase family; COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: mem:Memar_1359 glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase.
    
  0.552
EJG06625.1
Hypothetical protein.
       0.491
EJG07460.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR012818:IPR000878; KEGG: mem:Memar_0515 cobalt-precorrin-6Y C(5)-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating); TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core.
  
    0.466
EJG06884.1
PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651; KEGG: mem:Memar_1015 RimK domain-containing protein ATP-grasp; PFAM: ATP-grasp fold, RimK-type; SPTR: SSU ribosomal protein S6P modification protein.
  
  
 0.462
EJG06622.1
Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mem:Memar_1774 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein.
       0.429
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: high (88%) [HD]