STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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EJG06671.1Digeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (278 aa)    
Predicted Functional Partners:
EJG06066.1
Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
 
 
 0.898
carS
UPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
 
  
 0.853
EJG07862.1
Geranylgeranyl reductase; PFAM: Lycopene cyclase protein; FAD binding domain; TIGRFAM: geranylgeranyl reductase family; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR011777:IPR013027; KEGG: mbn:Mboo_1166 geranylgeranyl reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Geranylgeranyl reductase; TIGRFAM: Geranylgeranyl reductase, plant/prokaryotic.
 
 
 0.827
EJG07119.1
Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
    
 0.819
EJG07898.1
Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
 
 
 0.804
EJG06578.1
PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: mem:Memar_1816 geranyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Geranylgeranyl-diphosphate synthase / farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.744
EJG06670.1
PFAM: Protein of unknown function (DUF3160); KEGG: mba:Mbar_A2195 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.678
EJG07454.1
PFAM: von Willebrand factor type A domain; MCM2/3/5 family; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593:IPR002035:IPR011704; KEGG: mhu:Mhun_0291 magnesium chelatase, ChlI subunit; PFAM: von Willebrand factor, type A; ATPase associated with various cellular activities, AAA-5; SMART: von Willebrand factor, type A; ATPase, AAA+ type, core; SPTR: Protoporphyrin IX magnesium-chelatase.
 
  
 0.675
EJG06672.1
KEGG: mem:Memar_1696 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.649
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
    
 0.634
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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