STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06727.1PFAM: Glucose-6-phosphate isomerase (GPI); COGs: COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzyme; InterPro IPR010551; KEGG: mem:Memar_0485 glucose-6-phosphate isomerase; PFAM: Glucose-6-phosphate isomerase, prokarya; SPTR: Glucose-6-phosphate isomerase. (232 aa)    
Predicted Functional Partners:
EJG06843.1
Protein of unknown function DUF100; PFAM: Fructose-1,6-bisphosphatase; COGs: COG1980 fructose 1 6-bisphosphatase; InterPro IPR002803; KEGG: mbn:Mboo_1612 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, class V; SPTR: Putative uncharacterized protein.
     
 0.959
EJG07441.1
PFAM: Demethylmenaquinone methyltransferase; Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase; COGs: COG0269 3-hexulose-6-phosphate synthase and related protein; InterPro IPR001754:IPR005493; KEGG: mem:Memar_0744 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator; PFAM: Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase; Orotidine 5'-phosphate decarboxylase, core; SPTR: 3-hexulose-6-phosphate synthase.
 
 
  0.958
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
  0.956
fbp
Fructose-1,6-bisphosphatase class 1; PFAM: Fructose-1-6-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; HAMAP: Fructose-1,6-bisphosphatase; InterPro IPR000146; KEGG: mpi:Mpet_1687 inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 1.
     
  0.954
EJG07386.1
PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR017552:IPR001347; KEGG: mem:Memar_1507 sugar isomerase (SIS); PFAM: Sugar isomerase (SIS); SPTR: 3-hexulose-6-phosphate isomerase; TIGRFAM: 6-phospho 3-hexuloisomerase; manually curated.
 
 
 0.953
EJG06637.1
Sugar isomerase (SIS); PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347; KEGG: mem:Memar_0706 sugar isomerase (SIS); PFAM: Sugar isomerase (SIS); SPTR: 3-hexulose-6-phosphate isomerase.
 
 
 0.948
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006436; KEGG: mpl:Mpal_2790 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; SPTR: Glyceraldehyde-3-phosph [...]
    
 0.941
EJG08323.1
PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: mem:Memar_2487 ROK family protein; PFAM: ROK; SPTR: Glucokinase.
    
 0.936
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.935
aroA-2
Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
  
  
 0.934
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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