STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06757.1Cl- channel voltage-gated family protein; PFAM: CBS domain; Voltage gated chloride channel; COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644:IPR001807; KEGG: mem:Memar_1622 Cl-channel, voltage-gated family protein; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Cl-channel, voltage-gated family protein. (600 aa)    
Predicted Functional Partners:
EJG08255.1
PFAM: 2Fe-2S iron-sulfur cluster binding domain; Cysteine-rich domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001041:IPR004017:IPR004489; KEGG: mem:Memar_0220 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: Cysteine-rich region, CCG; Ferredoxin; SPTR: Thiol-driven fumarate reductase, iron-sulfur protein; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein.
     
 0.754
EJG06245.1
PFAM: Citrate transporter; TrkA-C domain; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: mpi:Mpet_2047 TrkA-C domain-containing protein; PFAM: Regulator of K+ conductance, C-terminal; Divalent ion symporter; SPTR: TrkA-C domain protein.
 
  
 0.681
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.646
EJG06224.1
Flavodoxin/nitric oxide synthase; InterPro IPR008254; KEGG: mem:Memar_2171 ArsR family transcriptional regulator; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Transcriptional regulator, ArsR family.
     
 0.607
EJG06756.1
PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mem:Memar_0700 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; manually curated.
     
 0.593
EJG07311.1
CoA-binding domain protein; PFAM: CoA binding domain; ATP-grasp domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR013650:IPR003781; KEGG: mem:Memar_2327 CoA-binding domain-containing protein; PFAM: CoA-binding; ATP-grasp fold, succinyl-CoA synthetase-type; SPTR: CoA-binding domain protein.
       0.559
EJG07854.1
CoA-binding domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR013650:IPR003781; KEGG: mpi:Mpet_1169 CoA-binding domain-containing protein; PFAM: CoA-binding; ATP-grasp fold, succinyl-CoA synthetase-type; SPTR: CoA-binding domain protein.
       0.559
EJG08073.1
PFAM: DHH family; DHHA1 domain; TrkA-N domain; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR003148:IPR001667:IPR003156; KEGG: mem:Memar_0397 TrkA domain-containing protein; PFAM: Regulator of K+ conductance, N-terminal; Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: TrkA-N domain protein.
 
     0.534
EJG08176.1
PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070:IPR004388; KEGG: mpl:Mpal_0134 SUA5/YciO/YrdC/YwlC family protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Sua5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC.
 
     0.505
EJG06795.1
KEGG: mbn:Mboo_1737 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.469
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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