STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG06768.1Conserved hypothetical protein CHP00268; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962:IPR005232; KEGG: mem:Memar_1612 ExsB family protein; PFAM: Asparagine synthase; SPTR: ExsB family protein; TIGRFAM: Conserved hypothetical protein CHP00268. (247 aa)    
Predicted Functional Partners:
EJG06801.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: AIR carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: mpl:Mpal_2200 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase.
 
  
 0.980
EJG06346.1
PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: mpl:Mpal_0261 hypothetical protein; PFAM: Protein of unknown function DUF111; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF111; Belongs to the LarC family.
  
 0.920
EJG06273.1
PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: mpi:Mpet_0163 hypothetical protein; PFAM: Protein of unknown function DUF111; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF111.
  
 0.914
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.839
EJG06769.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: ton:TON_0921 iron-molybdenum cofactor-binding protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Iron-molybdenum cofactor-binding protein.
       0.773
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.746
EJG07863.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: mhu:Mhun_1480 cobalt transport protein CbiM; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein.
 
    0.648
EJG07864.1
KEGG: mpi:Mpet_1870 cobalt transport protein CbiN; SPTR: Cobalt transport protein CbiN.
  
    0.585
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.585
rbcL
Ribulose bisphosphate carboxylase large chain; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
  0.540
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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