STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmERibosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (200 aa)    
Predicted Functional Partners:
EJG07819.1
PFAM: Nucleolar GTP-binding protein 1 (NOG1); TIGRFAM: small GTP-binding protein domain; COGs: COG1084 GTPase; InterPro IPR005225:IPR002917; KEGG: mbn:Mboo_2103 small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein; manually curated.
   
 
 0.989
EJG06393.1
PFAM: Putative snoRNA binding domain; COGs: COG1498 Protein implicated in ribosomal biogenesis Nop56p homolog; InterPro IPR002687; KEGG: mem:Memar_0541 pre-mRNA processing ribonucleoprotein, binding region; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; SPTR: rRNA biogenesis protein Nop56/Nop58.
 
 0.985
rpl30
PFAM: Ribosomal protein L30p/L7e; TIGRFAM: 50S ribosomal protein L30P, archaeal; COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR005997:IPR000517; KEGG: mem:Memar_0585 50S ribosomal protein L30P; PFAM: Ribosomal protein L30p/L7e, conserved region; SPTR: 50S ribosomal protein L30P; TIGRFAM: Ribosomal protein L30, archaeal.
   
 
 0.982
rps8e
PFAM: Ribosomal protein S8e; TIGRFAM: ribosomal protein S8.e; COGs: COG2007 Ribosomal protein S8E; HAMAP: 30S ribosomal protein S8e; InterPro IPR001047; KEGG: mpi:Mpet_2173 30S ribosomal protein S8e; PFAM: Ribosomal protein S8e; SPTR: 30S ribosomal protein S8e; TIGRFAM: Ribosomal protein S8e; manually curated.
  
 
 0.982
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
 
 0.959
EJG06694.1
KEGG: mem:Memar_1674 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.953
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
     
 0.947
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.946
eif6
Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
 
 0.942
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 0.941
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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