STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06863.1PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (non-peptidoglycan organisms); COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterPro IPR000534:IPR012280:IPR005676; KEGG: mem:Memar_1455 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD-binding; Semialdehyde dehydrogenase, dimerisation region; SPTR: Aspartate-semialdehyde dehydrogenase; TIGRFAM: Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking. (338 aa)    
Predicted Functional Partners:
EJG08253.1
PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: mpl:Mpal_0401 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; Belongs to the aspartokinase family.
 
 
 0.999
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.998
EJG07144.1
PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342; KEGG: mpl:Mpal_1993 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; SPTR: Homoserine dehydrogenase.
 
 0.998
EJG07549.1
PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: mpl:Mpal_1291 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
  0.984
EJG07550.1
PFAM: CBS domain; Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708:IPR000644; KEGG: mbn:Mboo_1272 hypothetical protein; PFAM: Protein of unknown function DUF39; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Putative uncharacterized protein.
    
  0.984
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
  
  
 0.942
EJG07184.1
PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: psl:Psta_1854 acetylornithine transaminase; PFAM: Aminotransferase class-III; SPTR: Acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.942
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
  
 0.922
pgk
PFAM: Phosphoglycerate kinase; COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: mbn:Mboo_2342 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase 2; Belongs to the phosphoglycerate kinase family.
  
 0.913
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 
 0.878
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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