STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06866.1PFAM: Domain of unknown function (DUF373); COGs: COG2237 membrane protein; InterPro IPR007254; KEGG: mem:Memar_1451 hypothetical protein; PFAM: Protein of unknown function DUF373; SPTR: Putative uncharacterized protein. (378 aa)    
Predicted Functional Partners:
EJG06867.1
Putative phosphoserine phosphatase; COGs: COG1340 Uncharacterized coiled-coil protein; KEGG: mbn:Mboo_1403 putative phosphoserine phosphatase; SPTR: Putative phosphoserine phosphatase.
 
     0.864
EJG06608.1
PFAM: Radical SAM superfamily; COGs: COG2108 conserved hypothetical protein related to pyruvate formate-lyase activation; InterPro IPR007197; KEGG: mem:Memar_1789 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein.
 
     0.746
EJG08302.1
Transcriptional regulator, XRE family; PFAM: Helix-turn-helix; COGs: COG1709 transcriptional regulator protein; InterPro IPR001387; KEGG: mem:Memar_2360 helix-turn-helix domain-containing protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family.
 
     0.681
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.658
atpE-2
V-type proton ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.648
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
     0.628
dtdA
D-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
     0.626
EJG07173.1
PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase.
  
     0.605
EJG06845.1
Hypothetical protein; PFAM: B-block binding subunit of TFIIIC; KEGG: mpl:Mpal_1540 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.604
EJG07992.1
Nucleotide binding protein, PINc; COGs: COG1439 nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module; KEGG: mbn:Mboo_2393 nucleotide binding protein, PINc; SPTR: Nucleotide binding protein, PINc.
  
     0.598
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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