STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06871.15-deoxyadenosylcobinamide phosphate nucleotidyltransferase; TIGRFAM: TIGR00454 family protein; COGs: COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase; KEGG: mem:Memar_1446 5-deoxyadenosylcobinamide phosphate nucleotidyltransferase; SPTR: Molybdenum cofactor guanylyltransferase. (209 aa)    
Predicted Functional Partners:
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.993
cobD
Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
  0.987
EJG06870.1
PFAM: Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: mem:Memar_1447 putative L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase.
 
     0.952
eif2b
Translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
 
     0.771
EJG06872.1
Conserved hypothetical protein CHP00300; PFAM: LOR/SDH bifunctional enzyme conserved region; TIGRFAM: TIGR00300 family protein; COGs: COG1915 conserved hypothetical protein; InterPro IPR007545:IPR005239; KEGG: mbn:Mboo_1408 LOR/SDH bifunctional protein; PFAM: LOR/SDH bifunctional enzyme conserved region; SPTR: LOR/SDH bifunctional enzyme conserved domain protein; TIGRFAM: Conserved hypothetical protein CHP00300.
 
     0.752
EJG07474.1
PFAM: Phosphatidylglycerophosphatase A; TIGRFAM: alpha-ribazole phosphatase CobZ; COGs: COG1267 Phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: mbn:Mboo_0702 phosphatidylglycerophosphatase A; PFAM: Phosphatidylglycerophosphatase A; SPTR: Phosphatidylglycerophosphatase A.
 
     0.688
EJG07473.1
UPF0284 protein; PFAM: Phosphoribosyltransferase; TIGRFAM: TIGR00303 family protein; COGs: COG2038 NaMN:DMB phosphoribosyltransferase; HAMAP: UPF0284 protein; InterPro IPR002805:IPR003200; KEGG: mpl:Mpal_1548 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like, core; SPTR: UPF0284 protein Mpal_1548; TIGRFAM:Nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase, putative; Belongs to the UPF0284 family.
 
     0.651
EJG06362.1
UPF0288 protein; TIGRFAM: putative methanogenesis marker protein 3; COGs: COG4070 peptidyl-prolyl cis-trans isomerase (rotamase) cyclophilin family; HAMAP: UPF0288 protein; InterPro IPR016466; KEGG: mbn:Mboo_2435 hypothetical protein; SPTR: UPF0288 protein Mboo_2435; TIGRFAM: Uncharacterised conserved protein UCP005852, methanogenesis; Belongs to the UPF0288 family.
  
     0.610
EJG06367.1
Methanogenesis marker protein 7; PFAM: Methyl-coenzyme M reductase operon protein C; TIGRFAM: putative methanogenesis marker protein 7; COGs: COG4052 Uncharacterized protein related to methyl coenzyme M reductase subunit C; InterPro IPR011312; KEGG: mem:Memar_2059 hypothetical protein; PFAM: Uncharacterised conserved protein UCP019164, methanogenesis; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised conserved protein UCP019164, methanogenesis.
  
     0.585
EJG08295.1
Protein of unknown function DUF105; PFAM: Cysteine-rich small domain; Adenosylcobinamide amidohydrolase; COGs: COG1865 conserved hypothetical protein; InterPro IPR002808:IPR007212; KEGG: mla:Mlab_0705 hypothetical protein; PFAM: Adenosylcobinamide amidohydrolase, CbiZ; Cysteine-rich small domain; SPTR: Putative uncharacterized protein.
 
     0.585
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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