STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG06911.1TIGRFAM: siroheme synthase, N-terminal domain; COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: mem:Memar_0979 siroheme synthase; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal. (213 aa)    
Predicted Functional Partners:
EJG06906.1
uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR006366; KEGG: mem:Memar_0984 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Uroporphyrinogen-III C-methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family.
 
 
 0.999
EJG07637.1
Cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: CbiX; COGs: COG2138 conserved hypothetical protein; InterPro IPR002762; KEGG: mem:Memar_1731 sirohydrochlorin cobaltochelatase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiX protein.
  
 
 0.999
EJG07466.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878; KEGG: mpi:Mpet_1755 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.990
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.982
EJG07649.1
COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: mbn:Mboo_0956 AsnC family transcriptional regulator; SMART: Transcription regulator, AsnC-type; SPTR: Putative transcriptional regulator, AsnC family.
 
  
 0.977
EJG06907.1
PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase; COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: mem:Memar_0983 porphobilinogen deaminase; PFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; SPTR: Hydroxymethylbilane synthase; TIGRFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase.
 
 
 0.969
hemL
PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; InterPro IPR005814:IPR004639; KEGG: mem:Memar_0982 glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase.
 
  
 0.957
EJG06909.1
PFAM: Delta-aminolevulinic acid dehydratase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: mem:Memar_0981 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.956
EJG07465.1
Precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878; KEGG: mem:Memar_0510 uroporphyrin-III C/tetrapyrrole methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core.
 
  
 0.875
EJG07636.1
Methanogenesis marker domain 9; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, putative; putative methanogenesis marker domain 9; COGs: COG4008 metal-binding transcription factor; InterPro IPR017671; KEGG: mem:Memar_1729 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Putative methanogenesis marker domain 9.
       0.848
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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