Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG06970.1UspA domain-containing protein; PFAM: Universal stress protein family; COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: mpl:Mpal_0780 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein. (141 aa)    
Predicted Functional Partners:
EJG06971.1
PFAM: CBS domain; COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: mbn:Mboo_1383 signal transduction protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Putative signal transduction protein with CBS domains.
  
    0.946
EJG06969.1
PFAM: Amidohydrolase family; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: mem:Memar_1195 amidohydrolase; PFAM: Amidohydrolase 1; SPTR: Amidohydrolase.
       0.905
EJG08099.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003594; KEGG: mem:Memar_1707 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; GAF; SMART: ATP-binding region, ATPase-like; GAF; SPTR: GAF sensor signal transduction histidine kinase.
     
 0.873
EJG08283.1
KEGG: mem:Memar_2322 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.785
EJG07694.1
PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal; COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR011549:IPR006401:IPR002734; KEGG: mem:Memar_2026 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; SPTR: 2, 5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one reductase; TIGRFAM:2,5-diamino-6-hydroxy-4-(5- phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific dea [...]
       0.708
EJG06598.1
PFAM: CBS domain; COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: mbn:Mboo_2229 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing protein.
  
    0.577
psmB
Proteasome endopeptidase complex, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
    0.551
EJG06331.1
Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR006674:IPR003607; KEGG: mem:Memar_2141 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase.
 
     0.498
EJG08131.1
UspA domain-containing protein; PFAM: Universal stress protein family; InterPro IPR006016; KEGG: htu:Htur_4298 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein.
  
   
 0.476
secG
Preprotein translocase subunit secG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
       0.472
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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