STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07006.1Ribosome biogenesis GTPase RsgA; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A; COGs: COG1162 GTPase; HAMAP: ribosome biogenesis GTPase RsgA; InterPro IPR004881; KEGG: mem:Memar_0890 ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; SPTR: Ribosome small subunit-dependent GTPase A; TIGRFAM: GTPase EngC. (368 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
     
 0.974
rps12
Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
   
   0.952
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.927
rps13
Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
    
   0.923
rps2
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005707; KEGG: mbn:Mboo_2215 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2P; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; Belongs to the universal ribosomal protein uS2 family.
 
 
   0.910
rps15
PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15; COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR012606:IPR000589; KEGG: mpi:Mpet_2006 ribosomal S13S15 domain-containing protein; PFAM: Ribosomal protein S13/S15, N-terminal; Ribosomal protein S15; SPTR: 30S ribosomal protein S15P/S13e.
  
   0.904
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
   0.895
rps14
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
    
   0.895
rps10
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
   0.895
rps19p
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.870
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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