| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJG06466.1 | EJG06470.1 | Metli_0498 | Metli_0502 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | 0.999 |
| EJG06466.1 | EJG07019.1 | Metli_0498 | Metli_1062 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | 0.478 |
| EJG06466.1 | EJG07239.1 | Metli_0498 | Metli_1283 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | PFAM: Uncharacterized protein conserved in archaea (DUF2111); COGs: COG4048 conserved hypothetical protein; InterPro IPR012029; KEGG: mem:Memar_1649 hypothetical protein; PFAM: Uncharacterised conserved protein UCP006557, signal transduction; SPTR: Putative uncharacterized protein. | 0.654 |
| EJG06466.1 | EJG07657.1 | Metli_0498 | Metli_1713 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0375 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | 0.993 |
| EJG06466.1 | mtrE | Metli_0498 | Metli_0496 | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. | 0.967 |
| EJG06470.1 | EJG06466.1 | Metli_0502 | Metli_0498 | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.999 |
| EJG06470.1 | EJG07019.1 | Metli_0502 | Metli_1062 | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | 0.479 |
| EJG06470.1 | EJG07239.1 | Metli_0502 | Metli_1283 | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | PFAM: Uncharacterized protein conserved in archaea (DUF2111); COGs: COG4048 conserved hypothetical protein; InterPro IPR012029; KEGG: mem:Memar_1649 hypothetical protein; PFAM: Uncharacterised conserved protein UCP006557, signal transduction; SPTR: Putative uncharacterized protein. | 0.651 |
| EJG06470.1 | EJG07654.1 | Metli_0502 | Metli_1710 | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.999 |
| EJG06470.1 | mtrE | Metli_0502 | Metli_0496 | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. | 0.991 |
| EJG07018.1 | EJG07019.1 | Metli_1061 | Metli_1062 | GAF domain protein; InterPro IPR003018; KEGG: mpi:Mpet_0436 putative GAF sensor protein; PFAM: GAF; SMART: GAF; SPTR: Putative GAF sensor protein. | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | 0.713 |
| EJG07018.1 | EJG07020.1 | Metli_1061 | Metli_1063 | GAF domain protein; InterPro IPR003018; KEGG: mpi:Mpet_0436 putative GAF sensor protein; PFAM: GAF; SMART: GAF; SPTR: Putative GAF sensor protein. | PFAM: DsrE/DsrF-like family; SirA-like protein; COGs: COG2044 peroxiredoxins; InterPro IPR003787; KEGG: mpi:Mpet_0434 DsrE family protein; PFAM: Sulphur relay, DsrE-like protein; SPTR: DsrE family protein. | 0.681 |
| EJG07018.1 | EJG07021.1 | Metli_1061 | Metli_1064 | GAF domain protein; InterPro IPR003018; KEGG: mpi:Mpet_0436 putative GAF sensor protein; PFAM: GAF; SMART: GAF; SPTR: Putative GAF sensor protein. | KEGG: mpi:Mpet_0433 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.498 |
| EJG07019.1 | EJG06466.1 | Metli_1062 | Metli_0498 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. | 0.478 |
| EJG07019.1 | EJG06470.1 | Metli_1062 | Metli_0502 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | PFAM: Methyl-coenzyme M reductase beta subunit, C-terminal domain; Methyl-coenzyme M reductase beta subunit, N-terminal domain; TIGRFAM: methyl-coenzyme M reductase, beta subunit; COGs: COG4054 Methyl coenzyme M reductase beta subunit; InterPro IPR003179; KEGG: mem:Memar_0617 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit; SPTR: Methyl-coenzyme M reductase, beta subunit; TIGRFAM: Methyl-coenzyme M reductase, beta subunit. | 0.479 |
| EJG07019.1 | EJG07018.1 | Metli_1062 | Metli_1061 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | GAF domain protein; InterPro IPR003018; KEGG: mpi:Mpet_0436 putative GAF sensor protein; PFAM: GAF; SMART: GAF; SPTR: Putative GAF sensor protein. | 0.713 |
| EJG07019.1 | EJG07020.1 | Metli_1062 | Metli_1063 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | PFAM: DsrE/DsrF-like family; SirA-like protein; COGs: COG2044 peroxiredoxins; InterPro IPR003787; KEGG: mpi:Mpet_0434 DsrE family protein; PFAM: Sulphur relay, DsrE-like protein; SPTR: DsrE family protein. | 0.853 |
| EJG07019.1 | EJG07021.1 | Metli_1062 | Metli_1064 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | KEGG: mpi:Mpet_0433 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.775 |
| EJG07019.1 | EJG07022.1 | Metli_1062 | Metli_1065 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | Hypothetical protein. | 0.562 |
| EJG07019.1 | EJG07239.1 | Metli_1062 | Metli_1283 | Protein of unknown function DUF169; PFAM: Uncharacterised ArCR, COG2043; COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: mpi:Mpet_0435 hypothetical protein; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein. | PFAM: Uncharacterized protein conserved in archaea (DUF2111); COGs: COG4048 conserved hypothetical protein; InterPro IPR012029; KEGG: mem:Memar_1649 hypothetical protein; PFAM: Uncharacterised conserved protein UCP006557, signal transduction; SPTR: Putative uncharacterized protein. | 0.492 |