STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07023.1GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; COGs: COG1247 Sortase and related acyltransferase; InterPro IPR000182; KEGG: mma:MM_1902 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative uncharacterized protein. (177 aa)    
Predicted Functional Partners:
EJG07184.1
PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: psl:Psta_1854 acetylornithine transaminase; PFAM: Aminotransferase class-III; SPTR: Acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.814
EJG07316.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR005672:IPR000515; KEGG: mpi:Mpet_1485 phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; Phosphate transport system [...]
       0.743
EJG07024.1
Regulatory protein MarR; PFAM: MarR family; InterPro IPR000835; KEGG: mma:MM_1903 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family.
  
  
 0.696
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
    
  0.684
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
    
  0.674
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
 
  
  0.608
EJG06134.1
Putative signal transduction histidine kinase; PFAM: Natural resistance-associated macrophage protein; 5TMR of 5TMR-LYT; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR011620; KEGG: mpi:Mpet_2152 signal transduction histidine kinase LytS; PFAM: Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SPTR: Signal transduction histidine kinase, LytS.
     
 0.566
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
    
  0.566
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.556
EJG08253.1
PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: mpl:Mpal_0401 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; Belongs to the aspartokinase family.
     
 0.533
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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