STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07139.1Hypothetical protein; PFAM: Uracil DNA glycosylase superfamily; COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; KEGG: mpi:Mpet_1152 hypothetical protein; SPTR: Putative uncharacterized protein. (165 aa)    
Predicted Functional Partners:
EJG07303.1
Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR000097:IPR004808:IPR005135; KEGG: rci:RCIX1223 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth.
  
 
 0.959
EJG07138.1
Hypothetical protein.
       0.773
EJG07140.1
KEGG: mhu:Mhun_1474 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.661
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.646
EJG07142.1
PFAM: Mechanosensitive ion channel; COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: mla:Mlab_0330 hypothetical protein; PFAM: Mechanosensitive ion channel MscS; SPTR: MscS Mechanosensitive ion channel.
       0.606
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
 
    0.601
EJG07141.1
KEGG: mla:Mlab_0329 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.595
uvrA
UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.544
EJG07744.1
PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR004607:IPR002376; KEGG: mem:Memar_1976 phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; TIGRFAM: Phosphoribosylglycinamide formyltransferase.
  
 
  0.540
EJG07293.1
PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: mem:Memar_1721 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein.
 
   
 0.472
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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