STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07145.1COGs: COG2061 ACT-domain-containing protein predicted allosteric regulator of homoserine dehydrogenase; KEGG: mbn:Mboo_1353 amino acid-binding ACT domain-containing protein; SPTR: Amino acid-binding ACT domain protein. (163 aa)    
Predicted Functional Partners:
EJG07143.1
COGs: COG1571 DNA-binding protein containing a Zn-ribbon domain; KEGG: mem:Memar_0972 hypothetical protein; SPTR: tRNA(Ile2) 2-agmatinylcytidine synthetase.
 
     0.890
EJG07144.1
PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342; KEGG: mpl:Mpal_1993 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; SPTR: Homoserine dehydrogenase.
       0.860
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.705
EJG07856.1
Exosortase EpsH-related protein; PFAM: Transmembrane exosortase (Exosortase_EpsH); COGs: COG4083 membrane protein; InterPro IPR019127; KEGG: mbn:Mboo_0910 cytochrome oxidase, subunit I, putative; PFAM: Exosortase EpsH-related; SPTR: Cytochrome oxidase, subunit I, putative.
  
     0.699
EJG07607.1
Flagellin domain protein; PFAM: Protein of unknown function (DUF1628); TIGRFAM: archaeal flagellin N-terminal-like domain; InterPro IPR013373:IPR012859; KEGG: mem:Memar_1218 hypothetical protein; PFAM: Protein of unknown function DUF1628; SPTR: Putative uncharacterized protein; TIGRFAM: Archaeal flagellin, N-terminal related.
  
     0.691
EJG07760.1
PFAM: RNA polymerase Rpb4; COGs: COG1460 conserved hypothetical protein; InterPro IPR005574; KEGG: mpl:Mpal_0548 RNA polymerase Rpb4; PFAM: RNA polymerase II, Rpb4; SPTR: RNA polymerase Rpb4.
  
     0.676
EJG06438.1
Protein of unknown function DUF106 transmembrane; PFAM: Integral membrane protein DUF106; COGs: COG1422 membrane protein; InterPro IPR002809; KEGG: mem:Memar_0589 hypothetical protein; PFAM: Protein of unknown function DUF106, transmembrane; SPTR: Putative uncharacterized protein.
  
     0.673
EJG08249.1
PFAM: Protein of unknown function (DUF552); COGs: COG2450 conserved hypothetical protein; InterPro IPR012426; KEGG: mpl:Mpal_0398 protein of unknown function DUF1621; PFAM: Protein of unknown function DUF1621; SPTR: Putative uncharacterized protein.
  
     0.661
EJG06117.1
PFAM: Kinase binding protein CGI-121; InterPro IPR007510; KEGG: mem:Memar_2502 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.656
EJG06998.1
COGs: COG3390 conserved hypothetical protein; KEGG: mem:Memar_1249 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.648
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.