STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07152.1PFAM: Inositol monophosphatase family; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: mpl:Mpal_2338 bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase; PFAM: Inositol monophosphatase; SPTR: Inositol-phosphate phosphatase. (258 aa)    
Predicted Functional Partners:
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
 0.992
EJG06586.1
PFAM: RNA polymerase Rpb6; InterPro IPR006110; KEGG: mbn:Mboo_2217 RNA polymerase Rpb6; PFAM: RNA polymerase Rpb6; SPTR: RNA polymerase Rpb6; manually curated.
  
   0.911
hisB
PFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: mpl:Mpal_1747 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase.
  
 
 0.855
EJG07316.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA; COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR011864:IPR005672:IPR000515; KEGG: mpi:Mpet_1485 phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: Phosphate ABC transporter, permease protein PstC; Phosphate transport system [...]
       0.848
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
 
 0.833
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
   
 
 0.826
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
 
 0.807
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.807
EJG07035.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: mpl:Mpal_1085 PfkB domain protein; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.786
rps10
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
 
 0.779
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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