STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07171.1AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. (188 aa)    
Predicted Functional Partners:
EJG06583.1
UPF0103/Mediator of ErbB2-driven cell motility-containing protein; PFAM: Memo-like protein; COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: mem:Memar_1811 hypothetical protein; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; SPTR: Putative uncharacterized protein; Belongs to the MEMO1 family.
    0.993
EJG07662.1
PFAM: Radical SAM superfamily; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR006638; KEGG: mem:Memar_1034 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
     0.951
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
     0.945
EJG07173.1
PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase.
       0.935
EJG07697.1
PFAM: Periplasmic binding protein; Radical SAM superfamily; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR002491; KEGG: mem:Memar_0026 radical SAM domain-containing protein; PFAM: Radical SAM; Periplasmic binding protein; SPTR: Radical SAM domain protein; manually curated.
     0.668
EJG07174.1
PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB.
  
    0.663
EJG07175.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: mpi:Mpet_2094 glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric.
       0.655
EJG07176.1
Methyltransferase type 11; PFAM: Methyltransferase domain; InterPro IPR013216; KEGG: mpi:Mpet_2525 type 11 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11.
       0.655
pheT
Phenylalanyl-tRNA synthetase beta chain; PFAM: tRNA synthetases class II core domain (F); tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase beta chain; InterPro IPR004531:IPR005146:IPR005147; KEGG: mem:Memar_0644 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase, B5; B3/B4 tRNA-binding domain; SPTR: Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic.
 
     0.450
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
     0.426
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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