| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJG07068.1 | EJG07173.1 | Metli_1111 | Metli_1217 | PFAM: S-adenosylmethionine synthetase (AdoMet synthetase); COGs: COG1812 S-adenosylmethionine synthetase; InterPro IPR002795; KEGG: mem:Memar_0838 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase (MAT), archaea; SPTR: Methionine adenosyltransferase. | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | 0.493 |
| EJG07068.1 | EJG07176.1 | Metli_1111 | Metli_1220 | PFAM: S-adenosylmethionine synthetase (AdoMet synthetase); COGs: COG1812 S-adenosylmethionine synthetase; InterPro IPR002795; KEGG: mem:Memar_0838 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase (MAT), archaea; SPTR: Methionine adenosyltransferase. | Methyltransferase type 11; PFAM: Methyltransferase domain; InterPro IPR013216; KEGG: mpi:Mpet_2525 type 11 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11. | 0.401 |
| EJG07171.1 | EJG07173.1 | Metli_1215 | Metli_1217 | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | 0.935 |
| EJG07171.1 | EJG07174.1 | Metli_1215 | Metli_1218 | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | 0.663 |
| EJG07171.1 | EJG07175.1 | Metli_1215 | Metli_1219 | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: mpi:Mpet_2094 glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric. | 0.655 |
| EJG07171.1 | EJG07176.1 | Metli_1215 | Metli_1220 | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | Methyltransferase type 11; PFAM: Methyltransferase domain; InterPro IPR013216; KEGG: mpi:Mpet_2525 type 11 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11. | 0.655 |
| EJG07171.1 | tgtA | Metli_1215 | Metli_1216 | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | 7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.945 |
| EJG07173.1 | EJG07068.1 | Metli_1217 | Metli_1111 | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | PFAM: S-adenosylmethionine synthetase (AdoMet synthetase); COGs: COG1812 S-adenosylmethionine synthetase; InterPro IPR002795; KEGG: mem:Memar_0838 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase (MAT), archaea; SPTR: Methionine adenosyltransferase. | 0.493 |
| EJG07173.1 | EJG07171.1 | Metli_1217 | Metli_1215 | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | 0.935 |
| EJG07173.1 | EJG07174.1 | Metli_1217 | Metli_1218 | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | 0.662 |
| EJG07173.1 | EJG07175.1 | Metli_1217 | Metli_1219 | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: mpi:Mpet_2094 glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric. | 0.662 |
| EJG07173.1 | EJG07176.1 | Metli_1217 | Metli_1220 | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | Methyltransferase type 11; PFAM: Methyltransferase domain; InterPro IPR013216; KEGG: mpi:Mpet_2525 type 11 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11. | 0.698 |
| EJG07173.1 | tgtA | Metli_1217 | Metli_1216 | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | 7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.959 |
| EJG07174.1 | EJG07171.1 | Metli_1218 | Metli_1215 | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | 0.663 |
| EJG07174.1 | EJG07173.1 | Metli_1218 | Metli_1217 | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | 0.662 |
| EJG07174.1 | EJG07175.1 | Metli_1218 | Metli_1219 | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: mpi:Mpet_2094 glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric. | 0.999 |
| EJG07174.1 | EJG07176.1 | Metli_1218 | Metli_1220 | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | Methyltransferase type 11; PFAM: Methyltransferase domain; InterPro IPR013216; KEGG: mpi:Mpet_2525 type 11 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11. | 0.773 |
| EJG07174.1 | tgtA | Metli_1218 | Metli_1216 | PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: mem:Memar_1283 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Sulfide dehydrogenase (Flavoprotein) subunit SudB. | 7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.663 |
| EJG07175.1 | EJG07171.1 | Metli_1219 | Metli_1215 | PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: mpi:Mpet_2094 glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric. | AMMECR1-domain protein; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family; COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: mem:Memar_1288 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1. | 0.655 |
| EJG07175.1 | EJG07173.1 | Metli_1219 | Metli_1217 | PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004; KEGG: mpi:Mpet_2094 glutamate synthase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric. | PFAM: PUA domain; TIGRFAM: uncharacterized domain 2; COGs: COG1549 Queuine tRNA-ribosyltransferase contain PUA domain; InterPro IPR002478:IPR004521; KEGG: mem:Memar_1286 PUA domain-containing protein; PFAM: Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: tRNA-archaeosine synthase. | 0.662 |