STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07202.1CheC, inhibitor of MCP methylation; PFAM: CheC-like family; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: mpl:Mpal_1855 CheC, inhibitor of MCP methylation; PFAM: CheC-like protein; SPTR: CheC, inhibitor of MCP methylation. (205 aa)    
Predicted Functional Partners:
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 0.999
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.994
EJG07201.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR010808:IPR 004105; KEGG: mem:Memar_0943 CheA signal transduction histidine kinases; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, P2 response regulator [...]
 
 0.992
EJG07199.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: mpl:Mpal_1858 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
 
 
 0.986
EJG08392.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: mem:Memar_0238 CheA signal transduction histidine kinases; PFAM: Signal transduction response regulator, receiver region; CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: Signal transduction response regulator, recei [...]
 
 0.977
EJG08393.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013163:IPR003660:IPR004089; KEGG: mem:Memar_0239 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache, type 2; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
 
 0.948
EJG08285.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mpi:Mpet_1620 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein.
 
 
 0.894
EJG06003.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mpi:Mpet_0205 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein.
 
 
 0.886
EJG08394.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mem:Memar_0240 putative CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Putative CheW protein.
 
 
 0.849
EJG06508.1
CheC, inhibitor of MCP methylation; PFAM: CheC-like family; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: mpi:Mpet_1206 MCP methylation inhibitor CheC; PFAM: CheC-like protein; SPTR: CheC, inhibitor of MCP methylation.
  
  
  0.819
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.