STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secFSecD/SecF/SecDF export membrane protein; Involved in protein export. (285 aa)    
Predicted Functional Partners:
secD
Preprotein translocase subunit SecD; Involved in protein export.
 
 0.999
srp54
Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
 
 0.779
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
  
 0.767
EJG06094.1
TIGRFAM: signal peptidase I, archaeal type; InterPro IPR001733; KEGG: mem:Memar_0046 peptidase S26B, signal peptidase; SPTR: Peptidase S26B, signal peptidase; TIGRFAM: Peptidase S26B, eukaryotic signal peptidase.
  
  
 0.726
EJG07229.1
PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; COGs: COG2231 Uncharacterized protein related to Endonuclease III; InterPro IPR003265; KEGG: mpi:Mpet_1694 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein.
       0.703
EJG07231.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin; InterPro IPR013766; KEGG: mbn:Mboo_1798 thioredoxin domain-containing protein; PFAM: Thioredoxin domain; SPTR: Thioredoxin domain.
       0.675
EJG07230.1
Thioredoxin domain-containing protein; PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766; KEGG: mbn:Mboo_1798 thioredoxin domain-containing protein; PFAM: Thioredoxin domain; SPTR: Thioredoxin domain.
       0.659
topA
DNA topoisomerase type IA central domain protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken s [...]
 
  
 0.636
EJG07228.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: mhu:Mhun_3173 L-fuculose phosphate aldolase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Class II aldolase/adducin-like protein.
 
     0.628
EJG06245.1
PFAM: Citrate transporter; TrkA-C domain; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037; KEGG: mpi:Mpet_2047 TrkA-C domain-containing protein; PFAM: Regulator of K+ conductance, C-terminal; Divalent ion symporter; SPTR: TrkA-C domain protein.
  
    0.612
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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