STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07305.1Nuclear protein SET; PFAM: SET domain; COGs: COG2940 Proteins containing SET domain; InterPro IPR001214; KEGG: mem:Memar_0660 nuclear protein SET; SMART: SET; SPTR: Nuclear protein SET. (162 aa)    
Predicted Functional Partners:
rpl40e
PFAM: Ribosomal L40e family; HAMAP: 50S ribosomal protein L40e; InterPro IPR001975; KEGG: mbn:Mboo_0238 50S ribosomal protein L40e; PFAM: Ribosomal protein L40e; SPTR: 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
    
  0.934
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.932
EJG08345.1
PFAM: Histone deacetylase domain; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mem:Memar_2236 histone deacetylase superfamily protein; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily.
  
 0.925
EJG08383.1
PFAM: DnaJ domain; InterPro IPR001623; KEGG: mem:Memar_0880 heat shock protein DnaJ domain-containing protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein.
   
 0.923
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
     
 0.874
rpoD
DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.774
EJG07530.1
PFAM: Protein kinase domain; COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442:IPR020635:IPR002290; KEGG: mpi:Mpet_2630 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: Serine/threonine protein kinase.
    
 0.741
EJG08052.1
PFAM: Protein kinase domain; COGs: COG0515 Serine/threonine protein kinase; InterPro IPR020635:IPR002290:IPR017442; KEGG: mem:Memar_1771 protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: Protein kinase.
    
 0.741
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
   
 
 0.706
EJG07919.1
PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterPro IPR007644:IPR007642:IPR007645; KEGG: mbn:Mboo_1934 DNA-directed RNA polymerase subunit beta''; PFAM: RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; SPTR: DNA-directed RNA polymerase; Belongs to the RNA polymerase beta chain family.
    
 
 0.687
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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