STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07355.1Protein serine/threonine phosphatase; PFAM: 5TMR of 5TMR-LYT; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR011620:IPR010822; KEGG: mem:Memar_2468 stage II sporulation E family protein; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SMART: Protein phosphatase 2C-related; SPTR: Stage II sporulation E family protein. (453 aa)    
Predicted Functional Partners:
EJG07354.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: pth:PTH_2273 anti-sigma regulatory factor; PFAM: ATP-binding region, ATPase-like; SPTR: Anti-sigma regulatory factor.
 
 0.995
EJG07356.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: mpi:Mpet_0954 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Putative anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 0.990
EJG07353.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: mbn:Mboo_1161 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma-factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 0.988
EJG08392.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: mem:Memar_0238 CheA signal transduction histidine kinases; PFAM: Signal transduction response regulator, receiver region; CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: Signal transduction response regulator, recei [...]
 
  
  0.980
EJG08100.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: mem:Memar_2467 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 0.959
EJG08186.1
Hypothetical protein; TIGRFAM: Chlamydial polymorphic outer membrane protein repeat; KEGG: mla:Mlab_1452 hypothetical protein; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 0.950
EJG07942.1
Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR000014:IPR001610:IPR003594:IPR 013656:IPR013767; KEGG: mpi:Mpet_0399 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; PAS fold; ATP-binding region, ATPase-like; SMART: Signal transduction response regula [...]
 
 
 0.948
EJG08266.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003594:IPR013655:IPR 013656; KEGG: mpi:Mpet_2338 multi-sensor signal transduction histidine kinase; PFAM: PAS fold-4; PAS fold-3; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; PAS; PAC motif; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS.
 
 
 0.940
EJG08313.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR001789:IPR000014:IPR001610:IPR003594:IPR 013655:IPR013767:IPR013656; KEGG: mpi:Mpet_0602 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; PAS fold-3; PAS fold; PAS fold-4; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; PAS [...]
 
 
 0.934
EJG07535.1
Putative PAS/PAC sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR001789:IPR013767:IPR013655:IPR 001610; KEGG: mhu:Mhun_1353 multi-sensor signal transduction histidine kinase; PFAM: PAS fold-3; Signal transduction response regulator, receiver region; PAS fold; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS.
 
 
 0.932
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.